A large-scale genetic study has provided strong evidence that the development of insulin resistance – a risk factor for type 2 diabetes and heart attacks and one of the key adverse consequences of obesity – results from the failure to safely store excess fat in the body.
People who carry variants in a particular gene have an increased preference for high fat food, but a decreased preference for sugary foods, according to a new study led by the University of Cambridge.
From middle-age, the brains of obese individuals display differences in white matter similar to those in lean individuals ten years their senior, according to new research led by the University of Cambridge. White matter is the tissue that connects areas of the brain and allows for information to be communicated between regions.
A study of 3.9 million adults published today in The Lancet has found that being overweight or obese is associated with an increased risk of premature death. The risks of coronary heart disease, stroke, respiratory disease and cancer are all increased. Overall, the excess risk of premature death (before age 70) among those who are overweight or obese is about three times as great in men as in women.
Theresa Marteau (Behaviour and Health Research Unit) discusses how to get people to consume less sugar.
People who live or work near to a greater number of takeaway outlets are more likely to eat more takeaway food and to be overweight, but new research indicates that neighbourhoods that are saturated with fast food outlets may be particularly unhealthy for people who are socioeconomically disadvantaged.
Overweight people make unhealthier food choices than lean people when presented with real food, even though both make similar selections when presented with hypothetical choices, according to research led by the University of Cambridge and published today in the journal eNeuro.
The Chancellor's recent announcement about a tax on sugary drinks is a step in the right direction towards fighting obesity, but we will need to use lot of different approaches simultaneously to make big changes, writes Dr Jean Adams from the Centre for Diet & Activity Research, Medical Research Council Epidemiology Unit.
The babies of obese women who develop gestational diabetes are five times as likely to be excessively large by six months of pregnancy, according to new research led by the University of Cambridge. The study, which shows that excessive fetal growth begins weeks before at-risk women are screened for gestational diabetes, suggests that current screening programmes may take place too late during pregnancy to prevent lasting health impacts on the offspring.
Genetic tests that provide an estimate of an individual’s risk of developing diseases such as lung cancer and heart disease do not appear to motivate a change in behaviour to reduce the risk, according to a study led by the University of Cambridge and published in The BMJ today.
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