Attack of the Crab Monsters (cropped)

Stopping tumour cells killing surrounding tissue may provide clue to fighting cancer

04 February 2016

Tumours kill off surrounding cells to make room to grow, according to new research from the University of Cambridge. Although the study was carried out using fruit flies, its findings suggest that drugs to prevent, rather than encourage, cell death might be effective at fighting cancer – contrary to how many of the current chemotherapy drugs work.

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Reset button (edited)

Reprogramming of DNA observed in human germ cells for first time

04 June 2015

A team of researchers led by the University of Cambridge has described for the first time in humans how the epigenome – the suite of molecules attached to our DNA that switch our genes on and off – is comprehensively erased in early primordial germ cells prior to the generation of egg and sperm.

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'Skin cancer selfies' (cropped)

Cancer-associated DNA changes exist in a quarter of normal skin cells

21 May 2015

Normal skin contains an unexpectedly high number of cancer-associated mutations, according to a study published in Science. The findings illuminate the first steps cells take towards becoming a cancer and demonstrate the value of analysing normal tissue to learn more about the origins of the disease.

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