Sleeping lady

Sleeping over eight hours a day associated with greater risk of stroke

25 February 2015

People who sleep for more than eight hours a day have an increased risk of stroke, according to a study by the University of Cambridge – and this risk doubles for older people who persistently sleep longer than average. However, the researchers say it is unclear why this association exists and call for further research to explore the link.

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Celestial bodies

04 February 2015

Astronomy and oncology do not make obvious bedfellows, but the search for new stars and galaxies has surprising similarities with the search for cancerous cells. This has led to new ways of speeding up image analysis in cancer research.

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First of new generation of cancer drugs granted European approval

18 December 2014

A new drug for ovarian cancer, developed by researchers at the University of Cambridge and AstraZeneca, has today become the first of new class of drugs, known as PARP-inhibitors, to be granted approval anywhere in the world. The drug, Lynparza, has been granted Marketing Authorisation from the European Commission.

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Metastatic Breast Cancer in Pleural Fluid

Drugging the undruggable: discovery opens up possibility of slowing cancer spread

12 November 2014

A trawl through a library of more than 50,000 ‘small molecules’ has identified a potential candidate to inhibit the spread of cancer cells throughout the body. Reported today in the journal Nature Communications, the molecule targets a mechanism of tumour development that had previously been considered ‘undruggable’– in other words, extremely difficult, if not impossible, to target with a drug – and could open the door to further promising new candidates.

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Cell nucleus before and after treatment with Remodelin

'Remodelling' damaged nuclei could lead to new treatments for accelerated ageing disease

01 May 2014

Scientists at the University of Cambridge have identified a key chemical that can repair the damage to cells which causes a rare but devastating disease involving accelerated ageing. As well as offering a promising new way of treating the condition, known as Hutchinson-Gilford Progeria Syndrome (HGPS), the discovery could help in the development of drugs against cancer and other genetic diseases and might also suggest ways to alleviate diseases that we associate with normal ageing.

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