Topic description and stories

New innovation hub aims to take a 'moon shot' at cystic fibrosis

18 Apr 2018

Almost 30 years on from the discovery of the genetic defect that causes cystic fibrosis, treatment options are still limited and growing antibiotic...

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The self-defence force awakens

04 Jul 2017

Our immune systems are meant to keep us healthy, but sometimes they turn their fire on us, with devastating results. Immunotherapies can help defend...

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Grobidon

Infections during pregnancy may interfere with key genes associated with autism and prenatal brain development

21 Mar 2017

If a mother picks up an infection during pregnancy, her immune system will kick into action to clear the infection – but this self-defence mechanism...

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DNA

Crohn’s disease risk and prognosis determined by different genes, study finds

09 Jan 2017

Researchers have identified a series of genetic variants that affect the severity of Crohn’s disease, an inflammatory bowel disease – but...

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Weight loss condition provides insight into failure of cancer immunotherapies

08 Nov 2016

A weight loss condition that affects patients with cancer has provided clues as to why cancer immunotherapy – a new approach to treating cancer by...

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Self-renewable killer cells could be key to making cancer immunotherapy work

26 Oct 2016

A small molecule that can turn short-lived ‘killer T-cells’ into long-lived, renewable cells that can last in the body for a longer period of time...

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Depressing fog

Anti-inflammatory drugs could help treat symptoms of depression, study suggests

18 Oct 2016

Anti-inflammatory drugs similar to those used to treat conditions such as rheumatoid arthritis and psoriasis could in future be used to treat some...

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Diabetes (rotated)

New approach to treating type 1 diabetes aims to limit damage caused by our own immune system

11 Oct 2016

Researchers at the University of Cambridge have taken the first step towards developing a new form of treatment for type 1 diabetes which, if...

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Yoshinori Ohsumi – a deserving winner of the Nobel Prize for physiology or medicine

03 Oct 2016

Yoshinori Ohsumi is a deserving winner of this year's Nobel Prize in physiology or medicine, whose work shows the value of basic research, writes...

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FAMIN or feast? Newly-discovered mechanism influences how immune cells ‘eat’ invading bacteria

01 Aug 2016

A new mechanism that affects how our immune cells perform – and hence their ability to prevent disease – has been discovered by an international team...

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‘Clogged-up’ immune cells help explain smoking risk for TB

24 Mar 2016

Smoking increases an individual’s risk of developing tuberculosis (TB) – and makes the infection worse – because it causes vital immune cells to...

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Aedes Albopictus mosquito (cropped, lightened)

Global consortium rewrites the ‘cartography’ of dengue virus

17 Sep 2015

An international consortium of laboratories worldwide that are studying the differences among dengue viruses has shown that while the long-held view...

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