Topic description and stories

Illustration of a woman getting a breast screening test

Back to BRCA: the discovery of a breast cancer risk gene

07 Oct 2024

In 1994, a landmark paper identified a gene – BRCA1 – that significantly increases the risk of breast and ovarian cancers when faulty. Thirty years...

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Leg sticking out from a white blanket

Genetics study points to potential treatments for restless leg syndrome

05 Jun 2024

Scientists have discovered genetic clues to the cause of restless leg syndrome, a condition common among older adults. The discovery could help...

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Cancer's climate innovation

04 Apr 2024

An enzyme inspired by brain cancer DNA that has the potential to slash greenhouse gas emissions from the production of nylon won the 2024 Cambridge...

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Illustration of brain anatomy

Largest genetic study of brain structure identifies how the brain is organised

17 Aug 2023

The largest ever study of the genetics of the brain – encompassing some 36,000 brain scans – has identified more than 4,000 genetic variants linked...

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Children playing tug of war

Largest ever DNA and health research programme for children and young people launches

25 Jul 2023

Cambridge researchers are helping launch a nationwide study for children and young people to unlock the power of our DNA.

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Should we allow genome editing of human embryos?

28 Feb 2023

A citizens’ jury of individuals whose lives have been affected by hereditary disease has voted in favour of asking the UK government to consider...

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Illustration of DNA molecules

DNA sequencing method lifts ‘veil’ from genome black box

23 Jan 2023

Many life-saving drugs directly interact with DNA to treat diseases such as cancer, but scientists have struggled to detect how and why they work –...

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Doctor examining a patient

Gone fishing: highly accurate test for common respiratory viruses uses DNA as ‘bait’

16 Jan 2023

A new test that ‘fishes’ for multiple respiratory viruses at once using single strands of DNA as ‘bait’, and gives highly accurate results in under...

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Toddler's hands touching tree bark

Children with rare genetic disorders more likely to be diagnosed with developmental, behavioural and mental health problems

03 Aug 2022

A major study of children with intellectual disabilities has highlighted the additional challenges that they often face, including a much-increased...

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3D illustration XY-chromosomes

One in 500 men carry extra sex chromosome, putting them at higher risk of several common diseases

10 Jun 2022

Around one in 500 men could be carrying an extra X or Y chromosome – most of them unaware – putting them at increased risk of diseases such as type 2...

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Merkel Cell Carcinoma

Largest study of whole genome sequencing data reveals new clues to causes of cancer

21 Apr 2022

DNA analysis of thousands of tumours from NHS patients has found a ‘treasure trove’ of clues about the causes of cancer, with genetic mutations...

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Weighing scales and tape measure

Many of us could carry up to 17kg of fat due to a change in a single gene

27 May 2021

New research has found that one in every 340 people might carry a mutation in a single gene that makes them more likely to have a greater weight from...

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