Topic description and stories

Brain cholesterol associated with increased risk of Alzheimer’s disease

07 May 2018

Researchers have shown how cholesterol – a molecule normally linked with cardiovascular diseases – may also play an important role in the onset and...

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Alzheimer's patients & carers

Advances in brain imaging settle debate over spread of key protein in Alzheimer’s

05 Jan 2018

Recent advances in brain imaging have enabled scientists to show for the first time that a key protein which causes nerve cell death spreads...

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Darwin Lecture Series

Genetics study adds further evidence that education reduces risk of Alzheimer’s disease

07 Dec 2017

The theory that education protects against Alzheimer’s disease has been given further weight by new research from the University of Cambridge, funded...

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Brain showing hallmarks of Alzheimer’s disease (plaques in blue)

Computer-designed antibodies target toxins associated with Alzheimer’s disease

22 Jun 2017

Researchers at the University of Cambridge have designed antibodies that target the protein deposits in the brain associated with Alzheimer’s disease...

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Older woman profile

Opinion: How epigenetics may help us slow down the ageing clock

12 May 2017

Why do we age when we get older? Epigenetics may hold the answer – but could it one day help us turn back the clock? Professor Wolf Reik from the...

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Scientists discover two repurposed drugs that arrest neurodegeneration in mice

20 Apr 2017

A team of scientists who a few years ago identified a major pathway that leads to brain cell death in mice, have now found two drugs that block the...

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Cambridge named as a centre for the UK Dementia Research Institute

20 Apr 2017

The University of Cambridge has been announced as one of the centres that will form the UK Dementia Research Institute (UK DRI) alongside Cardiff...

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Brain showing hallmarks of Alzheimer's disease (plaques in blue)

New imaging technique measures toxicity of proteins associated with Alzheimer’s and Parkinson’s diseases

23 Nov 2016

A new super-resolution imaging technique allows researchers to track how surface changes in proteins are related to neurodegenerative diseases such...

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Dementia: Catching the memory thief

21 Sep 2016

It's over a hundred years since the first case of Alzheimer’s disease was diagnosed. Since then we’ve learned a great deal about the protein ‘tangles...

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In healthy tissues, a gene expression signature associated with amyloid-beta and tau aggregation echoes the progression of AD well before the onset of the disease.

Gene signature in healthy brains pinpoints the origins of Alzheimer’s disease

10 Aug 2016

A specific gene expression pattern maps out which parts of the brain are most vulnerable to Alzheimer’s disease, decades before symptoms appear, and...

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Artist’s rendering of protein fibrils (in blue) and healthy proteins from computer simulations

Slow, slow, quick quick, slow: Scientists discover how proteins in the brain build up rapidly in Alzheimer’s disease

18 Jul 2016

Cambridge researchers have identified – and shown that it may be possible to control – the mechanism that leads to the rapid build-up of the disease-...

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New cases of dementia in the UK fall by 20% over two decades

19 Apr 2016

The UK has seen a 20% fall in the incidence of dementia over the past two decades, according to new research from England, led by the University of...

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