Mycobacterium tuberculosis

Gene discovery provides clues to how TB may evade the immune system

16 March 2015

The largest genetic study of tuberculosis (TB) susceptibility to date has led to a potentially important new insight into how the pathogen manages to evade the immune system. Published today in the journal Nature Genetics, the study advances understanding of the biological mechanisms involved in TB, which may open up new avenues to design efficient vaccines for its prevention.

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DNA (cropped)

Human genome includes 'foreign' genes not from our ancestors

12 March 2015

Many animals, including humans, acquired essential ‘foreign’ genes from microorganisms co-habiting their environment in ancient times, according to research published in the open access journal Genome Biology. The study challenges the conventional view that animal evolution relies solely on genes passed down through ancestral lines and suggests that, at least in some lineages, the process is still ongoing.

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Section of normal testes of a young man

Study finds increased DNA mutations in children of teenage fathers

18 February 2015

New research reveals that the sperm cells of adolescent boys have more than six times the rate of DNA mutations as the equivalent egg cells in adolescent girls, resulting in higher rates of DNA mutation being passed down to children of teenage fathers. The findings suggest that the risk of birth defects is higher in the children of teenage fathers as a consequence.

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