In the first genome-scale experiment of its kind, researchers have gained new insights into how a mouse embryo first begins to transform from a ball of unfocussed cells into a small, structured entity. Published in Nature, the single-cell genomics study was led by the European Bioinformatics Institute (EMBL-EBI) and the University of Cambridge.
A new technique that allows embryos to develop in vitro beyond the implantation stage (when the embryo would normally implant into the womb) has been developed by scientists at the University of Cambridge allowing them to analyse for the first time key stages of human embryo development up to 13 days after fertilisation. The technique could open up new avenues of research aimed at helping improve the chances of success of IVF.
Genetic ‘signatures’ of early-stage embryos confirm that our development begins to take shape as early as the second day after conception, when we are a mere four cells in size, according to new research led by the University of Cambridge and EMBL-EBI. Although they seem to be identical, the cells of the two day-old embryo are already beginning to display subtle differences.
Azim Surani (Wellcome Trust/Cancer Research UK Gurdon Institute) discusses gene editing of the human germline.
The journey from a single fertilised egg cell through to a baby delivered crying into the arms of its mother is one of the most beautiful and complex processes to occur in nature. We are only just beginning to understand the very earliest stages of life – when we are nothing more than a cluster of cells.
A new book tells, for the first time in full, the extraordinary story of drawings of embryos initially published in 1868. The artist was accused of fraud – but, copied and recopied, his images gained iconic status as evidence of evolution.
Researchers have captured the first 3D video of a living algal embryo turning itself inside out, from a sphere to a mushroom shape and back again. The results could help unravel the mechanical processes at work during a similar process in animals, which has been called the “most important time in your life.”
Looking at stem cells through physicists’ eyes is challenging some of our basic assumptions about the body’s master cells.
We know much about how embryos develop, but one key stage – implantation – has remained a mystery. Now, scientists from Cambridge have discovered a way to study and film this ‘black box’ of development.
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