Surgeons at work in an operating theatre

Scientists launch a pre-emptive strike on deadly post-transplant infection

23 February 2021

A potential new treatment to protect immunosuppressed patients from human cytomegalovirus (HCMV) has been discovered by scientists at the University of Cambridge. Their study shows that certain epigenetic inhibitors expose and help to destroy dormant HCMV infections, which often reactivate to cause serious illness and death in these vulnerable groups. Subject to clinical trials, their proposed ‘shock and kill’ treatment strategy offers hope to transplant patients across the world.

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HCMV

Silent killer

13 September 2013

Many of us are infected with a virus we’ll never clear. While we’re healthy, it’s nothing to worry about, but when our immune system is suppressed it could kill us.

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HIV-1 budding from a cultured cell

Offensive manoeuvres in the war against HIV

25 February 2013

Although anti-HIV drugs can significantly prolong life, patients must take the drugs for the rest of their lives. New approaches to therapeutics may hold the answer to finding a cure for HIV.

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