One hundred years ago, celebrations marking the end of the First World War were cut short by the onslaught of a devastating disease: the 1918-19 influenza pandemic.
Researchers at the University of Cambridge and the University of Oxford have discovered a new molecule that plays a key role in the immune response that is triggered by influenza infections. The molecule, a so-called mini viral RNA, is capable of inducing inflammation and cell death, and was produced at high levels by the 1918 pandemic influenza virus. The findings appeared in Nature Microbiology yesterday (September 17).