Vaccines could eventually be developed which could prevent the deaths hundreds of thousands of children a year from diarrhoea, according to an international expert in infectious disease.

Dr James P Nataro, a major researcher in vaccine development and global health, is speaking about the future of vaccine development in an open lecture on 2 March organised by the Gates Scholars Council.

The lecture, 'Vaccination in the Year 2100', will focus on the future of his field, looking forward to the day when vaccines will elicit a more natural form of resistance to infectious diseases.

Dr Nataro’s lab at the University of Maryland focuses particularly on understanding the nature of Ecoli and finding ways of preventing its spread. The World Health Organization says Ecoli accounts for several hundred million cases of diarrhoea and several ten of thousand deaths each year. The lab is also involved in the development of vaccines against potential bioterror agents, especially plague.

Dr Nataro is principal investigator on a $5.6m programme funded by the Bill & Melinda Gates Foundation to develop a faster and more precise test to diagnose the causes of diarrhoeal disease in developing countries, which account for at least 18% of deaths of children under five in the world. One of the main problems is identifying the particular pathogens that make children sick.

Dr Nataro, who is a professor in the Departments of Pediatrics, Microbiology & Immunology, Biochemistry & Molecular Biology, and Medicine, says current tests for establishing the cause of diarrhoeal disease and therefore the best treatment are “cumbersome” and expensive and so not suited to developing countries.

The programme’s goal is to develop mobile technology which allows the causes to be quickly and accurately diagnosed and could eventually lead to the development of suitable vaccines.

Dr Nataro’s talk is part of a series of public lectures which the Gates Scholars Council puts on during the academic year.

Ian Ralby, the Council’s external officer, says: “It is a delight to have Dr Jim Nataro with us this week as our final speaker in the Lent Term's Gates Distinguished Lecture Series. While the connection is coincidental, the Gates Scholars are pleased to welcome a leading researcher and expert in vaccine development and global health who is himself supported by the generosity of Bill & Melinda Gates. Dr Nataro's passion for his field makes him an engaging and enjoyable speaker, so this promises to be an excellent talk.”

The talk takes place on March 2 at 6pm in the Riley Auditorium of the Gillespie Centre at Clare College.
 


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