Articles about 'Wellcome Sanger Institute'

Human cells with acute myelocytic leukemia, shown with an esterase stain at 400x

Scientists develop new class of cancer drug with potential to treat leukaemia

26 April 2021

Scientists have made a promising step towards developing a new drug for treating acute myeloid leukaemia, a rare blood disorder. In a study published today in Nature, Cambridge researchers report a new approach to cancer treatment that targets enzymes which play a key role in translating DNA into proteins and which could lead to a new class of cancer drugs.

Genomics study identifies routes of transmission of coronavirus in care homes

03 March 2021

Genomic surveillance – using information about genetic differences between virus samples – can help identify how SARS-CoV-2 spreads in care home settings, whose residents are at particular risk, according to new research published today.

Q&A with Sharon Peacock, coronavirus variant hunter

22 February 2021

The UK is a world leader in sequencing SARS-CoV-2, the virus that causes COVID-19. Of all the coronavirus genomes that have been sequenced in the world, nearly half have been sequenced by COVID-19 Genomics UK Consortium (Cog-UK). The consortium began life on 4 March 2020 when Sharon Peacock, a professor of public health and microbiology at the University of Cambridge, emailed a handful of scientists and asked for their help.

Emerging intestinal villi with stem cells (green) supporting their growth

Gut research identifies key cellular changes associated with childhood-onset Crohn’s Disease

07 December 2020

Scientists have tracked the very early stages of human foetal gut development in incredible detail, and found specific cell functions that appear to be reactivated in the gut of children with Crohn’s Disease.

Transmission electron micrograph of SARS-CoV-2 virus particles, isolated from a patient

Cambridge-led SARS-CoV-2 genomic surveillance consortium receives £12.2 million

16 November 2020

The COVID-19 Genomics UK (COG-UK) Consortium has been backed by the Department for Health and Social Care Testing Innovation Fund to expand whole genome sequencing of positive SARS-CoV-2 virus samples to map how COVID-19 spreads and evolves. The £12.2M funding will facilitate the genome sequencing capacity needed to meet the increasing numbers of COVID-19 cases expected in the UK this winter.