First of new generation of cancer drugs granted European approval

18 December 2014

A new drug for ovarian cancer, developed by researchers at the University of Cambridge and AstraZeneca, has today become the first of new class of drugs, known as PARP-inhibitors, to be granted approval anywhere in the world. The drug, Lynparza, has been granted Marketing Authorisation from the European Commission.

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Stem cells show auxeticity; the nucleus expands, rather than thins, when it's stretched

Stem cell physical

10 October 2014

Looking at stem cells through physicists’ eyes is challenging some of our basic assumptions about the body’s master cells.

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Cell nucleus before and after treatment with Remodelin

'Remodelling' damaged nuclei could lead to new treatments for accelerated ageing disease

01 May 2014

Scientists at the University of Cambridge have identified a key chemical that can repair the damage to cells which causes a rare but devastating disease involving accelerated ageing. As well as offering a promising new way of treating the condition, known as Hutchinson-Gilford Progeria Syndrome (HGPS), the discovery could help in the development of drugs against cancer and other genetic diseases and might also suggest ways to alleviate diseases that we associate with normal ageing.

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Mini-livers show promise to reduce animal use in science

26 February 2014

Cambridge research that has for the first time successfully grown “mini-livers” from adult mouse stem cells has won the UK’s international prize for the scientific and technological advance with the most potential to replace, reduce or refine the use of animals in science (the 3Rs).

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