Articles about 'Centre for Trophoblast Research'

Researchers at one of the busiest maternity hospitals in the world aim to help more women survive complications giving birth.

Professor Kathy Niakan talks about why it’s vital to take a multidisciplined approach to understanding the urgent challenges posed by reproduction today – and introduces our Spotlight on some of this work, highlighted in the latest issue of Cambridge's Horizons magazine.

The first stages of placental development take place days before the embryo starts to form in human pregnancies. This new finding highlights the importance of healthy placental development in pregnancy, and could lead to future improvements in fertility treatments such as IVF, and a better understanding of placental-related diseases in pregnancy.

Changes occur in the placenta in older pregnant mothers leading to a greater likelihood of poor health in their male offspring, a study in rats has shown. 

Exercise immediately prior to and during pregnancy restores key tissues in the body, making them better able to manage blood sugar levels and lowering the risk of long term health problems, suggests new research carried out in mice.

Researchers say that new ‘mini-placentas’ – a cellular model of the early stages of the placenta – could provide a window into early pregnancy and help transform our understanding of reproductive disorders. Details of this new research are published today in the journal Nature.

Smoking, lack of exercise, bad diet and our genes are all well-known risk factors for heart disease, cancer and diabetes. But, as researchers are beginning to understand, the environment in the womb as we first begin to grow may also determine our future.

Homerton Fellow Dr Michelle Oyen explains why she has dedicated her working life to investigating why pregnancies go wrong.

Scientists at the University of Cambridge have succeeded in growing miniature functional models of the lining of the womb (uterus) in culture. These organoids, as they are known, could provide new insights into the early stages of pregnancy and conditions such as endometriosis, a painful condition that affects as many as two million women in the UK.

Eating a high fat and high sugar diet when pregnant leads to metabolic impairments in both the mother and her unborn child, which may 'program' them for potential health complications later in life, a study in mice has shown.