CRISPR-Cas9 genome editing can lead to unintended mutations at the targeted section of DNA in early human embryos, researchers have revealed. This highlights the need for further research into the effects of CRISPR-Cas9 genome editing, especially when used to edit human DNA in laboratory research.
The decision about if and when to have children can be one of the most significant many people will ever make. But – for those who have the choice – what influences come into play, and how have these changed over time?
We’re used to the idea that as adults we have some control over our destiny: what we eat and drink and how much we exercise can affect our health. But the risks of heart disease and diabetes can be programmed much earlier – even before we are born.
The first stages of placental development take place days before the embryo starts to form in human pregnancies. This new finding highlights the importance of healthy placental development in pregnancy, and could lead to future improvements in fertility treatments such as IVF, and a better understanding of placental-related diseases in pregnancy.
Mitochondrial therapy in complicated pregnancies lowers the chance of cardiovascular problems in the offspring.
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